Beyond excess, beyond ethics, beyond science . . . Enter a terrifying new experiment in pain from Eisner Award nominee Cullen Bunn (The Sixth Gun, Basilisk) and acclaimed illustrator Jes s Herv s (The Empty Man)! Dr. Carrie Reynolds was a veteran trauma surgeon with a godlike mastery of muscle and bone. But outside the operating room, her rigidly ordered life spiraled into chaos when her daughter, Heather-a recovering plastic surgery addict-suddenly disappeared, only to mysteriously reemerge in a catatonic state, her vocal cords removed . . . the latest in a series of victims scarred by a battery of brazenly cruel medical procedures that have baffled police and left an alarming number of once-ordinary citizens maimed, mutilated, or dead on arrival. Deep beneath the streets of Carrie's city, a new kind of underground hospital has just opened its doors . . . and, once inside, there are no rules, no oaths, and no taboos too deep to not to be broken. Together, a new class of surgeon has sworn to pierce the final threshold of accepted medical orthodoxy one incision at a time. The scalpel is their tool. The alleys are their operating theater. Murder is their medicine. And only Carrie can stop what they're planning next . . .